Natural Ginkgo Biloba Extract Powder For Cerebral And Microcirculation Improvement

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Natural Ginkgo Biloba Extract Powder For Cerebral And Microcirculation Improvement

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Product Details:

Place of Origin:	China
Brand Name:	CONBA
Certification:	GMP, CEP, GEP(CCCMHPIE), Kosher, Halal, ISO9000, ISO14000.
Model Number:	Che

Payment & Shipping Terms:

Minimum Order Quantity:	25kg
Packaging Details:	25kg Drum

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Detailed Product Description

FlavonolGlycosides:	MIN24%	TerpeneLactones:	MIN6%
Ginkgolic Acid:	<10ppm	Grade:	Pharmaceutical And Food
Packaging:	Drum	Type:	Herbal Extract
High Light:	ginkgo biloba bulk powder , pure ginkgo biloba powder

Natural Ginkgo Biloba Extract Powder For Cerebral And Microcirculation Improvement 0

CONBA^® Ginkgo Biloba Extract: USP40 24/6 Ginkgo Acid<1ppm, EP9.0 24/6 Ginkgo Acid<1ppm, Water soluble 24/6 1g/10ml,
Injection solution GA>2.2% GB>1.2% GC>1.2%

Chung HS et al, Journal of Ocular Pharmacology and Theraputics, 1999 Jun;15(3):233-40.

Part 4

Ginkgo biloba extract significantly increased end diastolic velocity (EDV) in the ophthalmic artery (OA) (baseline vs GBE-treatment; 6.5 /- 0.5 vs 7.7 /- 0.5 cm/sec, 23% change, p=0.023), with no change seen in placebo (baseline vs GBE-treatment; 7.2 /- 0.6 vs 7.1 /- 0.5 cm/sec, 3% change, p=0.892)

Flavonol aglycone

Flavonol aglycone	R1	R2	R3	R4
Kaempferol	H	H	H	H
Quercetin	OH	H	H	H
Isorhamnetin	OCH3	H	H	H

Terpene lactones

Terpene lactones	R1	R2
Ginkgolide A	H	H
Ginkgolide B	OH	H
Ginkgolide C	OH	OH

CHP SPECIFICATION SHEET

Item	Specification	Test Method
Appearance	Light yellow-brown powder	Visual
Identification
Identification A	Should conform Chp2015	TLC
Identification B	Should conform Chp2015	HPLC
Test
Limit of Ginkgolic Acid	NMT 10mg/kg	HPLC
Sophoricoside	Should be negative	HPLC
Loss on drying	NMT 5.0%	Limit test
Residue on ignition	NMT 0.8%	Limit test
Mesh	100% through 80 mesh	-
Heavy metal	Should conform Chp2015	AAS
Free Aglycone
Quercetin	NMT 10 mg/kg	HPLC
Kaempferol	NMT 10 mg/kg	HPLC
Isorhamnetin	NMT 4 mg/kg	HPLC
Apex area ratio
Q: K	0.8-1.2	HPLC
I: Q	>0.15	HPLC
Microbiological limit
Aerobic plate count	NMT 10cfu/g	Limit test
Mold&Yeast	NMT 10cfu/g	Limit test
E.Coli	Negative	Limit test
Assay
Content of flavonol glycosides	24%MIN	HPLC
Quercetin	/	HPLC
Kaempferol	/	HPLC
Isorhamnetin	/	HPLC
Terpene lactones	6.0%MIN	HPLC
Bilobalides	/	HPLC
Ginkgolides A	/	HPLC
Ginkgolides B	/	HPLC
Ginkgolides C	/	HPLC

Application:

Ginkgo leaf extract is used to improve mental performance, increase the pain-free walking distance in peripheral arterial occlusive disease, and for vertigo and tinnitus. Other indications include (age-associated) cognitive impairment and quality of life improvement in mild dementia. Ginkgo leaf extracts may help to prevent symptoms related to altitude sickness.