ChP2015 Ginkgo Biloba Standardized Extract Bright Yellow Brown Powder

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Ginkgo Biloba Extract (10)

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ChP2015 Ginkgo Biloba Standardized Extract Bright Yellow Brown Powder

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Product Details:

Place of Origin:	China
Brand Name:	CONBA
Certification:	GMP, CEP, GEP(CCCMHPIE), Kosher, Halal, ISO9000, ISO14000.
Model Number:	ChP

Payment & Shipping Terms:

Minimum Order Quantity:	25kg
Packaging Details:	25kg Drum

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Detailed Product Description

FlavonolGlycosides:	24%MIN	Terpene Lactones:	6.0%MIN
Limit Of Ginkgolic Acid:	NMT 10mg/kg	Sophoricoside:	Should Be Negative
Loss On Drying:	NMT 5.0%	Residue On Ignition:	NMT 0.8%
High Light:	standardized ginkgo biloba , ginkgo standardized extract

ChP2015 Ginkgo Biloba Standardized Extract Bright Yellow Brown Powder 0

CONBA^® Ginkgo Biloba Extract: USP40 24/6 Ginkgo Acid<1ppm, EP9.0 24/6 Ginkgo Acid<1ppm, Water soluble 24/6 1g/10ml,
Injection solution GA>2.2% GB>1.2% GC>1.2%

Ginkgo Biloba Standardized Extract Chp 2015

YuzhouWuet al, Pharmacology, Original Paper Planta Med 2007; 73(7): 624-628

Part 2

We designed this study to test the effects of GBE on distal left anterior descending coronary artery (LAD) blood flow and endothelium-dependent brachial artery flow-mediated dilation (FMD) in patients with Coronary Artery Disease (CAD).

Flavonol aglycone

Flavonol aglycone	R1	R2	R3	R4
Kaempferol	H	H	H	H
Quercetin	OH	H	H	H
Isorhamnetin	OCH3	H	H	H

Terpene lactones

Terpene lactones	R1	R2
Ginkgolide A	H	H
Ginkgolide B	OH	H
Ginkgolide C	OH	OH

Specification Chp2015

Item	Specification	Test Method
Appearance	Light yellow-brown powder	Visual
Identification
Identification A	Should conform Chp2015	TLC
Identification B	Should conform Chp2015	HPLC
Test
Limit of Ginkgolic Acid	NMT 10mg/kg	HPLC
Sophoricoside	Should be negative	HPLC
Loss on drying	NMT 5.0%	Limit test
Residue on ignition	NMT 0.8%	Limit test
Mesh	100% through 80 mesh	-
Heavy metal	Should conform Chp2015	AAS
Free Aglycone
Quercetin	NMT 10 mg/kg	HPLC
Kaempferol	NMT 10 mg/kg	HPLC
Isorhamnetin	NMT 4 mg/kg	HPLC
Apex area ratio
Q: K	0.8-1.2	HPLC
I: Q	>0.15	HPLC
Microbiological limit
Aerobic plate count	NMT 10cfu/g	Limit test
Mold&Yeast	NMT 10cfu/g	Limit test
E.Coli	Negative	Limit test
Assay
Content of flavonol glycosides	24%MIN	HPLC
Quercetin	/	HPLC
Kaempferol	/	HPLC
Isorhamnetin	/	HPLC
Terpene lactones	6.0%MIN	HPLC
Bilobalides	/	HPLC
Ginkgolides A	/	HPLC
Ginkgolides B	/	HPLC
Ginkgolides C	/	HPLC

Application:

Ginkgo leaf extract is used to improve mental performance, increase the pain-free walking distance in peripheral arterial occlusive disease, and for vertigo and tinnitus. Other indications include (age-associated) cognitive impairment and quality of life improvement in mild dementia. Ginkgo leaf extracts may help to prevent symptoms related to altitude sickness.